Workshop

October 27 (Tuesday) 18:00-20:00 Venue: Orion (5th floor)

ICEEP Workshop

Demystifying AI: The Application of Machine Learning, Artificial Intelligence and Algorithms to Equine Exercise Science

Panelists: Peta Hitchens, Glenn Van Steenkiste, Elin Hernlund

Prospective Outline:

Prof. Hitchens

  1. The basics
    1. What can you use AI for?
    2. What questions should you ask when evaluating an algorithm
    3. Terminology/nomenclature
  2. Performance metrics
    1. Sensitivity vs. Specificity: Balancing false negatives and false positives
    2. Positive Predictive Value (PPV) and Negative Predictive Value (NPV)
    3. Receiver Operating Characteristic (ROC) curves and Area Under the Curve (AUC)
    4. Rare events like EASD

Dr. Van Steenkiste

  1. How to create an algorithm
    1. Available commercial programs vs. programmer input (translating equine domain knowledge into code)
  2. Evaluating how rigorously an AI model was built and tested
    1. The modeling process – datasets for training/modeling vs. unseen validation datasets (and avoiding data leakage across horses)
    2. How to teach or guide it; inputting data (feature engineering vs. raw data)
    3. Identifying and avoiding bias (handling class imbalance, confounding variables, and using Explainable AI / XAI to audit model decision-making)
    4. The danger of overfitting (why high lab accuracy can fail in the field)

Prof. Hernlund

  1. Next steps
    1. What can we use AI for?
    2. What questions should you, the end-user ask?
    3. AI as an agent that can assist you
    4. Creating benchmarking datasets
October 27 (Tuesday) 18:00-20:00 Venue: Cosmos Hall (3rd floor)

ICEEP Workshop title: Interpretation of exercise ECGs

Format: Facilitated discussions with a panel of experts leading the topics.

Duration: 2 hours

Goals:

  • 1- Update the attendees on the work done on guidelines for equine ECGs by various groups
  • 2- Discuss challenges and potential solutions around the methods used to acquire and analyze exercising ECGs in horses.

Panel of experts:

-Prof. Léguillette      -Prof. van Loon      -Prof. Navas      -Prof. Franklin      - Prof. Buhl

-Dr. van Erck             -Dr. Ter Woort         -Dr. Nath

Contributors Dr. Frippiat, Dr Marr & Prof Jeevaratnam

Structure of the workshop:

  • 1-A summary of the ECVSMR round table on equine performance assessment will be presented by Dr. Frippiat (15mins).
  • 2-A summary of the ECG expert group’s work & Launch of “ECG-user community Delphi-based survey” presented by Celia Marr & Kamalan Jeevaratnam (15 mins)
  • 3-The challenges of the acquisition and interpretation of exercising ECGs in horses (all disciplines) will be introduced by Prof. Léguillette and a discussion will be opened, starting with a round of comments by the panelists and an interactive discussion with the attendees covering the specific objectives below (30 mins).

Specific objectives for the analysis of exercising ECGs:

Specific details covered for the analysis of exercising ECGs:

  1. What % of RR interval should be used to determine prematurity of PDs for various intensity of exercise?
  2. Arrhythmias are now often described based on morphology rather than describing them by origin. Is there a consensus for this and if so, can we standardize the description of the morphology of the arrhythmic complexes.
  3. How are we defining compensatory vs non compensatory pauses following PDs during strenuous exercise?
  4. What are the criteria to diagnose PAF (Duration and differences with short bursts of PDs for example)?

* The clinical significance of these arrhythmias will not be the focus of the workshop but can be mentioned as a “future direction”.

October 27 (Tuesday) 18:00-20:00 Venue: Subaru (5th floor)

Workshop Title: Advancing prevention of tendinopathy in the horse

Remit for the workshop - facilitated discussion rather than new presentations by speakers.

Expected duration: 2 hours (30 mins initial summary followed 3x30mins (90 mins totals) on each of the topics listed below).

Proposed Chairs:

  • Professor Roger Smith, Royal Veterinary College
    Background: More than 35 years experience in tendon research focussed on undertaking the pathogenesis and developing an effective preventative strategy.
  • Dr. Yoshinori Kasashima, Japan Racing Association
    Background: Former Director of the Equine Research Institute of the JRA with many years experience in both research and clinical investigations on racehorse tendinopathy.

Structure of the workshop

Summary of the scope of the workshop by Professor Roger Smith - The following key areas for the prevention of tendinopathy will be summarised in a short initial presentation and then each discussed by RKS, YK, and another relevant expert in the area who is attending the conference (TBD). In addition, each topic will be opened to questions/comments from the floor:

  • 1) Identifying the horse at risk
    1. Epidemiological risk factor modelling
      Overview: Risk factors that have been identified associated with tendinopathy and their application to prevention
    2. Genetics of tendon disease
      Overview: Evidence for the genetic basis of tendon disease and response to exercise in humans (and horses)
    3. Early detection of clinical disease
      Overview: A preventative strategy for more severe disease, centred on the current and future technologies
      • Imaging – ultrasound (eg quantitative ultrasound, ultrasound tissue characterisation, Doppler imaging), advanced imaging (MRI, CT, and PET)
      • Wearables
      • Functional tests – eg limb stiffness, tendon stiffness measurements (elastography)
      • Molecular markers, including currently available blood tests
  • 2) Exercise programmes to minimise the risk of injury
    1. Are there training methods to reduce the frequency of tendinopathy
      Overview: Using exercise physiological principles to model appropriate exercise programmes for competition horses and in rehabilitation.
    2. Creating a resilient tendon during growth through exercise
      Overview: Tendon responses to exercise programmes during growth – what is practical and does ‘conditioning’ work?
  • 3) Targetting exercise-driven degeneration
    Overview: The effects of exercise in the adult and biological approaches that can reduce the cumulation of age-related degeneration